{"id":73074,"date":"2025-08-26T10:34:27","date_gmt":"2025-08-26T07:34:27","guid":{"rendered":"https:\/\/icia.ro\/?page_id=73074"},"modified":"2026-01-14T14:32:45","modified_gmt":"2026-01-14T12:32:45","slug":"zeodeliver","status":"publish","type":"page","link":"https:\/\/icia.ro\/en\/zeodeliver\/","title":{"rendered":"ZEODELIVER"},"content":{"rendered":"<p><strong>Title<\/strong>: Natural zeolites as a platform for controlled release drug delivery systems<\/p>\n<p><strong>Acronym<\/strong>: ZEODELIVER<\/p>\n<p><strong>Domain<\/strong>: Sanatate &#8211; Biomateriale<\/p>\n<p><strong>Program<\/strong>: 5.8 European and international cooperation, 5.8.3 Subprogram Bilateral \/ multilateral mobility project Romania \u2013 Turkey<\/p>\n<p><strong>Contract no<\/strong>: 3BMTR\/2025<\/p>\n<p><strong>Thematic Fields<\/strong>: Health: Biomaterials<\/p>\n<p><strong>Financing Authority<\/strong>: Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI), Romania<\/p>\n<p><strong>Partner Romania<\/strong><br \/>\nINCDO-INOE 2000, Research Institute for Analytical Instrumentation<br \/>\nDonath Street 67, RO-400293 Cluj-Napoca, Romania<br \/>\nEmail: oana.cadar@icia.ro<br \/>\nProject responsible: Dr. Oana Cadar<\/p>\n<p><strong>Partner Turkey<\/strong><br \/>\nIstanbul University-Cerrahpa\u015fa<br \/>\nAvcilar Campus 1, TR-34320 Istanbul, Turkey<br \/>\nE-mail: selins@iuc.edu.tr<br \/>\nProject responsible: Prof. Dr. Selin Sahin Sevgili<\/p>\n<p><strong>Project duration: <\/strong>01.04.2025-31.12.2026<\/p>\n<p><strong>General objectives<\/strong><br \/>\nO1. Development of innovative zeolite-antibiotic-biopolymer biomaterials for controlled oral delivery of antibiotics<br \/>\nO2. Fostering scientific cooperation and joint research activities between the Romanian partner (INCDO INOE 2000, Research Institute for Analytical Instrumentation) and the Turkish partner (Istanbul University-Cerrahpa\u015fa) to increase the number of researchers and institutions involved in international collaborations and to enhance Romania&#8217;s participation in the EU Framework Programme for Research and Innovation.<\/p>\n<p><strong>Abstract<\/strong><br \/>\nThe continuous improvement of existing drugs and the development of therapeutic systems in order to reduce the administered dose, extend the half-life, improve the drug delivery and direct the drug to the target area while minimizing side effects are matters of public concern worldwide. The project team comprises a Romanian research institute (INCDO INOE 2000, Research Institute for Analytical Instrumentation Subsidiary, ICIA) and a Turkish university (Istanbul University-Cerrahpa\u015fa, IUC). The project creates a complementary team of specialists in the modification of natural zeolites for different applications (ICIA) and the development of intelligent biomaterials using statistical approaches (IUC); it provides a solid basis for the use of natural clinoptilolite-based zeolites in the development of innovative solutions that respond the current demand for effective and safe medical therapies. The project aims to promote successful bilateral scientific research and cooperation by developing biomaterials by combining zeolite-antibiotic systems with biopolymers to facilitate antibiotic stability and controlled release. The project will promote scientific collaboration between the two teams, increasing the number of researchers and institutions involved in international collaborations and Romania&#8217;s participation in the EU Framework Programme for Research and Innovation.<\/p>\n<hr \/>\n<p><strong>Development of natural zeolites as a platform for controlled release of active substances (2025)<\/strong><\/p>\n<ul>\n<li>A1.1. Collaborative visit: Turkish researchers to Romania. Preparation and optimization of zeolite-antibiotic systems<\/li>\n<li>A1.2 Collaborative visit: Romanian researchers to Turkey. Development and preparation of ZEODELIVER (I) systems<\/li>\n<li>A1.3. Dissemination and reporting<\/li>\n<\/ul>\n<p><strong>Obtained results \u2013 Stage 1<\/strong><\/p>\n<ul>\n<li>optimized natural zeolites;<\/li>\n<li>experimental report and characterization of optimized materials;<\/li>\n<li>zeolite-antibiotic systems;<\/li>\n<li>interim report on the development and optimization of ZEODELIVER systems;<\/li>\n<li>hybrid zeolite-natural alginate microcapsules loaded with antibiotic;<\/li>\n<li>hybrid zeolite-natural chitosan microcapsules loaded with antibiotic<\/li>\n<\/ul>\n<p><strong>ISI papers<\/strong><\/p>\n<ol>\n<li>\u0130. Toprak\u00e7\u0131, E. Kurtulba\u015f, Z. Ci\u011fero\u011flu, O. Cadar, S. \u015eahin, Facile ultrasound-assisted synthesis of heterogeneous g-C3N4\/ZnO nanocomposite for tetracycline adsorption from aqueous solution. Colloids and Surfaces a Physicochemical and Engineering Aspects, 2025, 725, 137519, doi:10.1016\/j.colsurfa.2025.137519, IF=5,4.<\/li>\n<\/ol>\n<p><strong>Participation at scientific events<\/strong><\/p>\n<ol>\n<li>D. Scurtu, D. Simedru, S. \u015eahin, O. Cadar, <em>Modification of natural zeolites through acid and base treatments: A comparative study<\/em>, 8 thInternational Conference on Emerging Technologies in Materials Engineering, EmergeMAT, 06-07 October 2025, Bucharest, Romania, e-poster, <a href=\"https:\/\/imnr.ro\/wp\/en\/8th-edition-international-conference-emergemat\/\">https:\/\/imnr.ro\/wp\/en\/8th-edition-international-conference-emergemat\/<\/a>.<\/li>\n<li>S. \u015eahin, E. Kurtulba\u0219, O. Cadar, <em>Encapsulation of amoxicillin into thermally treated clinoptilolite-based zeolite-alginate microparticles with ionic gelation<\/em>, 9th International Antalya Scientific Research and Innovative Studies Congress, 20-23 November, 2025, Antalya, Turkey -prezentare oral\u0103, <a href=\"https:\/\/www.izdas.org\/antalyakongresi\">https:\/\/www.izdas.org\/antalyakongresi<\/a>.<\/li>\n<li>S. \u015eahin, I. Toprak\u00e7\u0131, O. Cadar, <em>Design and optimization of doxycycline-loaded natural zeolite-alginate hybrid microparticles<\/em>, 9th International Antalya Scientific Research and Innovative Studies Congress, 20-23 November, 2025, Antalya, Turkey &#8211; prezentare oral\u0103, <a href=\"https:\/\/www.izdas.org\/antalyakongresi\">https:\/\/www.izdas.org\/antalyakongresi<\/a>.<\/li>\n<\/ol>\n<p><strong>Invited lectures<\/strong><\/p>\n<ol>\n<li>\u201cFrom Istanbul to Cluj-Napoca: Research, Innovation and Collaboration\u201d, Prof. Dr. Selin Sahin Sevgili, Cluj-Napoca<\/li>\n<\/ol>\n<p><strong>Working visits conducted during the bilateral project<\/strong><\/p>\n<ol>\n<li>Collaborative visit: Turkish researchers to Romania, Prof. Dr. Selin Sahin Sevgili, Assist Prof. Dr. Ebru Kurtulbas and Dr. \u0130rem Toprak\u00e7\u0131 &#8211; 14.07-18.07.2025<\/li>\n<li>Collaborative visit: Romanian researchers to Turkey, Dr. Oana Cadar, Dr. Dorina Simedru and Dr. Bogdan Angyus &#8211; 15.09-20.09.2025<\/li>\n<\/ol>\n<hr \/>\n<p><strong>Other information<\/strong><br \/>\nDr. Oana Cadar<br \/>\nContact: oana.cadar@icia.ro<\/p>","protected":false},"excerpt":{"rendered":"<p>Title: Natural zeolites as a platform for controlled release drug delivery systems Acronym: ZEODELIVER Domain: Sanatate &#8211; Biomateriale Program: 5.8 European and international cooperation, 5.8.3 Subprogram Bilateral \/ multilateral mobility project Romania \u2013 Turkey Contract no: 3BMTR\/2025 Thematic Fields: Health: Biomaterials Financing Authority: Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI), Romania [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ZEODELIVER - INCDO INOE 2000 ICIA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/icia.ro\/zeodeliver\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ZEODELIVER - INCDO INOE 2000 ICIA\" \/>\n<meta property=\"og:description\" content=\"Title: Natural zeolites as a platform for controlled release drug delivery systems Acronym: ZEODELIVER Domain: Sanatate &#8211; 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