by icia icia

Pharmacogenomic impact of the determination of VKORC1 and CYP2C9 genes over the efficacy, safety and costs of the anticoagulant treatment, TROMBOGEN

Objectives:
to investigate the pharmacogenomic status of the patients, from both geno- andphenotypic point of view;
to reveal the polymorphism of the CYP2C9 and VKORC1 genes, and alsoof the genes involved in the thrombophilia phenomenon (Factor V Leiden, FII G20210A, PAI-1 4G/5G, MTHFR C677T and A1298C) and the possible relationship between the presence of these polymorphisms and the response to acenocumarol treatment;

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by icia icia

Development of spectrometric methods for identifying and tracking sources and pollution potential using analysis of trace rare earth,

Objectives:
The purpose of the project is the development and validation of complex analytical methods that can provide very useful information on pollution sources and their potential of pollution (especially tailings and ponds), methods based on mass spectrometry with inductively coupled plasma (ICP-MS), for determination of isotopic ratios and rare earth, and X-ray diffraction (XRD) to determine the mineralogy.

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